l-Nebiviololinium chloride dihydrate

نویسندگان

  • Gisbert Tuchalski
  • Andre Hänsicke
  • Günther Reck
  • Franziska Emmerling
چکیده

The hydro-chloride salt of chiral l-nebivolol {systematic name: (+)-(R,S,S,S)-bis-[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxy-ethyl]ammonium chloride dihydrate}, C(22)H(26)F(2)NO(4) (+)·Cl(-)·2H(2)O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half-chair conformations. Hydrogen bonds between the cation, anions and water mol-ecules contribute to the formation of layers parallel to the ac plane.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of various electrolytes on control release of bio-molluscicides loaded in alginate as crosslinked matrices

Background and Objective: To assess the control release of bio-molluscicides (Crude Ferula asafoetida and their active component ferulic acid) loaded in alginates as binding matrix. Methodology: Sodium alginate, an anionic block copolymer of β-D-mannuronic acid and α-L-guluronic acid, is a readily available, non-toxic polysaccharide its property to form gel with divalent and multivalent cations...

متن کامل

Coupling of Amines, Dialkyl acetylenedicarboxylaes and Formaldehyde Promoted by Copper (II) Chloride: An Efficient Synthesis of Polysubstituted Dihydro-2-oxopyrrols

An environmental friendly synthetic route for copper (II) chloride dihydrate catalyzed one-pot multicomponentsynthesis of biologically active high substituted dihydro-2-oxypyrroles has developed. The non-toxic, low-cost catalyst and eco-friendly and good to high yields are the notable benefits for the efficient synthesis of these products.

متن کامل

Interaction between cholesterol and calcium ions in solution.

Dialysis rates of cholesterol, calcium chloride dihydrate and of their mixture in 90% aqueous dioxane through Visking cellulose membrane were characterized by half-escape times (t1/2) of 2.2, 1.0 and 10.5 hours, respectively. Slow dialysis rate observed with the mixture was due to complex formation between four molecules of cholesterol and two molecules of calcium chloride dihydrate, molecular ...

متن کامل

3-Hydr­oxy-1,2,3,9-tetra­hydro­pyrrolo[2,1-b]quinazolin-4-ium chloride dihydrate: (+)-vasicinol hydro­chloride dihydrate from Peganum harmala L

The title compound, C(11)H(13)N(2)O(+)·Cl(-)·2H(2)O, the dihydrate of (+)-vasicinol hydro-chloride, is a pyrrolidinoquinazoline alkaloid. It was isolated from the ethyl acetate fraction of the leaves of Peganum harmala L. The pyrrolidine ring has an envelope conformation with the C atom at position 2 acting as the flap and the C atom at position 3, carrying the hydroxyl substituent, has an S co...

متن کامل

Effects of some parameters affecting the crystallization rate of calcium sulfate dihydrate in sodium chloride solution

Crystallization of calcium sulfate dihydrate (CaSO4.2H2O) in sodium chloride solutions at different supersaturation (δ = 1.2–2), pH =3, ionic strength (I = 0.5 M) and at 80°C was studied. The influence of aluminum and magnesium nitrates having very low concentrations (10 mol dm) on the rate of crystallization at different supersaturation was investigated. The rate of crystallization was found t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 64  شماره 

صفحات  -

تاریخ انتشار 2007